Sildenafil, included in Kamagra 100mg, belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. It is prescribed to adult males who have erectile dysfunction, commonly known as impotence. It occurs when a guy is unable to get or maintain a hard, erect penis suited for sexual engagement. Erectile dysfunction (ED) is the inability of males to achieve and keep an erect penis stiff enough to allow sexual intercourse. This medication works by relaxing the blood arteries in the penis, enabling blood to flow into the penis while you are sexually aroused.
Sildenafil works in the penis by suppressing PDE-5 and increasing nitric oxide (NO) activity. The erection of the penis is caused by the production of nitric oxide (NO) during sexual stimulation, which activates the enzyme guanylate cyclase. This causes an increase in cyclic guanosine monophosphate (cGMP), which causes smooth muscle relaxation and blood flow to the penis.